The school was established in 1976 and caters to approximately 900 students from Year 7 to Year 12. The College became an Independent Public School in 2015. The catchment area for the school is Gosnells, Huntingdale and Southern River. Feeder schools include Gosnells, Ashburton Drive, Seaforth, Huntingdale, Wirrabirra and Southern River Primary Schools.
Southern River College runs an academic and general education program: this includes Academic En-richment 7 to 12, ATAR and Vocational Education Pathways and STEM option programs in mechatronics and electronics. The College operates Inspire programs in Music, Netball and Soccer. Southern River College provide support programs via their Teaching and Learning Centre (TLC), Literacy and Numeracy Development Classes and Specialist Autism Extension Program (SALP).
Funding from the State Government to enable the upgrade of the Science and Technology blocks, a new gym, Performing Arts hall, SALP (Specialist Autism Learning Program) building upgrade, an additional uncover area, lecture theatre, and new basketball and netball courts. The upgrade is expected to cost $8.4 million and completed by late 2020.
- "Department of Education Schools online". 2010. Retrieved 18 September 2011.